{"id":21,"date":"2018-09-28T00:31:47","date_gmt":"2018-09-28T00:31:47","guid":{"rendered":"https:\/\/mma.ccny.cuny.edu\/?page_id=21"},"modified":"2020-04-11T22:50:26","modified_gmt":"2020-04-12T02:50:26","slug":"misson","status":"publish","type":"page","link":"https:\/\/mma.ccny.cuny.edu\/?page_id=21","title":{"rendered":"Rationale and Research Goals"},"content":{"rendered":"<p><span class=\"firstLetter\">T<\/span>he specific longstanding research goals of the CUNY Macromolecular Assemblies Institute involve basic research with applications primarily to human health, energy\u00a0 transfer, and agriculture.\u00a0 Our faculty-led teams focus on macromolecular targets such as proteins, nucleic acids, lipids, and carbohydrates, with specific goals that include the following:<\/p>\n<ul>\n<li>to identify and characterize new molecular targets for drug design<\/li>\n<li>to delineate disease-related macromolecular signals of cellular metabolism<\/li>\n<li>to understand protein-nucleic acid interactions in animals, plants, and viruses<\/li>\n<li>to characterize the structure of macromolecular assemblies associated with microbial virulence and cellular resistance to chemotherapy<\/li>\n<li>to design polymeric biomedical materials for metabolic sensing and drug delivery<\/li>\n<li>to design self-assembled materials for light harvesting, imaging, and sensor applications<\/li>\n<li>to identify natural polymer complexes that promote resistance of plants to microbial pathogens and other environmental stresses<\/li>\n<li>to develop the technological infrastructure to attain these goals<\/li>\n<\/ul>\n<p>These research goals are pursued using three distinct but related strategies: discovery of structure-function relationships for molecular machines, simulation of macromolecular structures, and bio-inspired design of functionally robust assemblies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The specific longstanding research goals of the CUNY Macromolecular Assemblies Institute involve basic research with applications primarily to human health, energy\u00a0 transfer, and agriculture.\u00a0 Our faculty-led teams focus on macromolecular targets such as proteins, nucleic acids, lipids, and carbohydrates, with specific goals&hellip;<span class=\"read-more\"><a href=\"https:\/\/mma.ccny.cuny.edu\/?page_id=21\">Read More &raquo;<\/a><\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/mma.ccny.cuny.edu\/index.php?rest_route=\/wp\/v2\/pages\/21"}],"collection":[{"href":"https:\/\/mma.ccny.cuny.edu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mma.ccny.cuny.edu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mma.ccny.cuny.edu\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mma.ccny.cuny.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=21"}],"version-history":[{"count":7,"href":"https:\/\/mma.ccny.cuny.edu\/index.php?rest_route=\/wp\/v2\/pages\/21\/revisions"}],"predecessor-version":[{"id":525,"href":"https:\/\/mma.ccny.cuny.edu\/index.php?rest_route=\/wp\/v2\/pages\/21\/revisions\/525"}],"wp:attachment":[{"href":"https:\/\/mma.ccny.cuny.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=21"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}